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Glossary
Pharmacogenomics

What is Pharmacogenomics?

Pharmacogenomics is the study of how genes affect a person's response to drugs, enabling personalized medication selection and dosing based on genetic profiles. This field combines pharmacology (the science of drugs) with genomics (the study of genes and their functions) to develop effective, safe medications tailored to a person's genetic makeup. Pharmacogenomic testing can identify genetic variations that influence drug metabolism, effectiveness, and risk of adverse reactions. For example, testing for variations in the CYP2D6 gene can determine how quickly a person metabolizes certain antidepressants, pain medications, or heart medications, allowing doctors to adjust dosages accordingly.

Why pharmacogenomics matters

  • Reduces adverse drug reactions: Identifies patients at risk for severe side effects before medication is prescribed, preventing potentially dangerous reactions
  • Optimizes medication effectiveness: Helps select drugs most likely to work for an individual based on their genetic profile
  • Personalizes dosing: Enables precise dosage adjustments based on how an individual's body processes specific medications

How Solace can help

A Solace advocate can help you understand pharmacogenomic testing options, navigate insurance coverage for genetic testing, and coordinate with your healthcare providers to implement personalized medication strategies. Advocates can also assist in interpreting test results and ensuring this information is properly incorporated into your medical records for future prescribing decisions.